Publicaties WCN-studies: prof. dr. J.H. Cornel

• Individual lifetime benefit from low-dose colchicine in patients with chronic coronary artery diseaseEuropean Journal of Preventive Cardiology - Mosterd, dr. A.; Cornel, prof. dr. J.H.; Koudstaal, dr. S.; Beelen, drs. D.P.W. - LoDoCo2 - ASCVD July 2023
• Drivers of mortality in patients with chronic coronary disease in the low-dose colchicine 2 trialInt J Cardiol - Abstract - Mosterd, dr. A.; Cornel, prof. dr. J.H.; Ronner, dr. E.; Prins, drs. F.J. - LoDoCo2 - ASCVD December 2022
• The Effect of Years-Long Exposure to Low-Dose Colchicine on Renal and Liver Function and Blood Creatine Kinase Levels: Safety Insights from the Low-Dose Colchicine 2 (LoDoCo2) TrialClinical drug investigation - Mosterd, dr. A.; Cornel, prof. dr. J.H. - LoDoCo2 - ASCVD October 2022
• Colchicine in Patients With Chronic Coronary Disease in Relation to Prior Acute Coronary SyndromeJournal of the American College of Cardiology - Fiolet, dr. A. [inactief]; Mosterd, dr. A.; Eck, dr. J.W.M. van; Beek, drs. E. van; Hartog, drs. F.R. den [inactief]; Cornel, prof. dr. J.H. - LoDoCo2 - ASCVD August 2021
• Efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomized trialsEuropean Heart Journal - Fiolet, dr. A. [inactief]; Mosterd, dr. A.; Cornel, prof. dr. J.H. - LoDoCo2 - ASCVD February 2021
• Colchicine Attenuates Inflammation Beyond the Inflammasome in Chronic Coronary Artery Disease: A LoDoCo2 Proteomic SubstudyCirculation - Abstract - Fiolet, dr. A. [inactief]; The, dr. S.H.K. [inactief]; Mosterd, dr. A.; Cornel, prof. dr. J.H. - LoDoCo2 - ASCVD August 2020
• Colchicine in Patients with Chronic Coronary DiseaseNew England Journal of Medicine - Abstract - Mosterd, dr. A.; Fiolet, dr. A. [inactief]; The, dr. S.H.K. [inactief]; Lenderink, dr. T.; Hoogslag, drs. P.A.M.; Jerzewski, dr. A. [inactief]; Nierop, drs. P.R.; Swart, drs. H.P.; Schaap, dr. J.; Kuijper, dr. A.F.M.; Hessen, dr. M.W.J. van; Dirksen, dr. M.T.; Alings, dr. A.M.W.; Schut, drs. A.; Cornel, prof. dr. J.H. - LoDoCo2 - ASCVD August 2020
• Short-term effect of low-dose colchicine on inflammatory biomarkers, lipids, blood count and renal function in chronic coronary artery disease and elevated high-sensitivity C- reactive proteinPLoS One - Abstract - Fiolet, dr. A. [inactief]; Mosterd, dr. A.; Cornel, prof. dr. J.H. - LoDoCo2 - ASCVD August 2020
• The effect of low-dose colchicine in patients with stable coronary artery disease: The LoDoCo2 trial rationale, design, and baseline characteristics.Am Heart J - Abstract - Fiolet, dr. A. [inactief]; Schut, drs. A.; Mosterd, dr. A.; Cornel, prof. dr. J.H. - LoDoCo2 - ASCVD October 2019
• Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trialThe Lancet - Abstract - Cornel, prof. dr. J.H. - HARMONY - Diabetes mellitus October 2018
• Inhibition of Interleukin-1b by Canakinumab and Cardiovascular Outcomes in Patients With Chronic Kidney DiseaseJ Am Coll Cardiol - Abstract - Cornel, prof. dr. J.H. - CANTOS - ASCVD May 2018
• Antiinflammatory Therapy with Canakinumab for Atherosclerotic DiseaseN Engl J Med - Abstract - Cornel, prof. dr. J.H. - CANTOS - ASCVD August 2017
• Secondary Prevention of Cardiovascular Disease in Patients with Type 2 Diabetes: International Insights from the TECOS TrialCirculation - Abstract - Cornel, prof. dr. J.H. - TECOS - ASCVD June 2017
• Safety of Sitagliptin in Patients with Type 2 Diabetes and Chronic Kidney Disease: Outcomes from TECOSDiabetes Obes Metab - Abstract - Cornel, prof. dr. J.H. - TECOS - ASCVD April 2017
• Clinically significant bleeding with low-dose rivaroxaban versus aspirin, in addition to P2Y12 inhibition, in acute coronary syndromes (GEMINI-ACS-1): a double-blind, multicentre, randomised trialLancet - Abstract - Cornel, prof. dr. J.H. - GEMINI - ASCVD March 2017
• Relationship of Platelet Reactivity With Bleeding Outcomes During Long-Term Treatment With Dual Antiplatelet Therapy for Medically Managed Patients With Non-ST-Segment Elevation Acute Coronary SyndromesJournal of the American Heart Association - Cornel, prof. dr. J.H. - Trilogy - ASCVD November 2016
• Effect of Sitagliptin on Kidney Function and Respective Cardiovascular Outcomes in Type 2 Diabetes: Outcomes From TECOSDiabetes Care - Abstract - Cornel, prof. dr. J.H. - TECOS - ASCVD October 2016
• Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Clinical Trial.JAMA Cardiol. - Abstract - Cornel, prof. dr. J.H. - TECOS - ASCVD May 2016
• Validation of BARC Bleeding Criteria in Patients With Acute Coronary Syndromes: The TRACER Trial.J Am Coll Cardiol - Abstract - Cornel, prof. dr. J.H. - TRA-CER - ASCVD May 2016
• Long-term outcomes for women versus men with unstable angina/non-ST-segment elevation myocardial infarction managed medically without revascularization: insights from the TaRgeted platelet Inhibition to cLarify the Optimal strateGy to medicallY manage Acute Coronary Syndromes trialAm Heart J - Abstract - Cornel, prof. dr. J.H. - Trilogy - ASCVD October 2015
• Impact of chronic kidney disease on long-term ischemic and bleeding outcomes in medically managed patients with acute coronary syndromes: Insights from the TRILOGY ACS Trial.Eur Heart J Acute Cardiovasc Care - Abstract - Cornel, prof. dr. J.H. - Trilogy - ASCVD July 2015
• Glycoprotein IIb/IIIa Receptor Inhibitors in Combination With Vorapaxar, a Platelet Thrombin Receptor Antagonist, Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes (from the TRACER Trial).Am J Cardiol - Abstract - Cornel, prof. dr. J.H. - TRA-CER - ASCVD May 2015
• Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial.Am Heart J - Abstract - Cornel, prof. dr. J.H. - APPRAISE-2 - ASCVD April 2015
• Impact of smoking status on platelet function and clinical outcomes with prasugrel vs. clopidogrel in patients with acute coronary syndromes managed without revascularization: Insights from the TRILOGY ACS trial.Am Heart J - Abstract - Cornel, prof. dr. J.H. - Trilogy - ASCVD July 2014
• Effects of vorapaxar on platelet reactivity and biomarker expression in non-ST-elevation acute coronary syndromes. The TRACER Pharmacodynamic Substudy.Thromb Haemost - Abstract - Cornel, prof. dr. J.H. - TRA-CER - ASCVD May 2014
• Platelet function during extended prasugrel and clopidogrel therapy for patients with ACS treated without revascularization: the TRILOGY ACS platelet function substudy.JAMA - Abstract - Cornel, prof. dr. J.H. - Trilogy - ASCVD November 2012
• Apixaban after acute coronary syndrome in patients with heart failure: insights from the APPRAISE-2 trial.Eur Heart J - Cornel, prof. dr. J.H. - APPRAISE-2 - ASCVD September 2012
• Lenient versus strict rate control in patients with atrial fibrillationN Engl J Med - Abstract - Bosker, dr. H.A. [inactief]; Alings, dr. A.M.W.; Cornel, prof. dr. J.H.; Tukkie, dr. R.; Kuijper, dr. A.F.M.; Tuininga, dr. Y.S. - RACE II - Arrhythmia April 2010
• Rationale and design of the dal-OUTCOMES trial: efficacy and safety of dalcetrapib in patients with recent acute coronary syndromeAm Heart J - Abstract - Hof, prof. dr. A.W. J. van 't; Alings, dr. A.M.W.; Lok, dr. D.J.A.; Liem, dr. A.H.; Kragten, dr. J.A.; Bronzwaer, drs. P.N.A. [inactief]; Cornel, prof. dr. J.H.; Freericks, M.P.; Hamer, drs. B.J.B.; Hamraoui, drs. K.; Hoedemaker, drs. G. [inactief]; Kuijper, dr. A.F.M.; Linssen, dr. G.C.M.; Louwerenburg, drs. J.W. [inactief]; Nierop, drs. P.R.; Oomen, drs. A. [inactief]; Plomp, drs. J.; Pos, drs. L.; Eck, dr. J.W.M. van; Willems, dr. F.F. - Dal-OUTCOMES - ASCVD December 2009
• Plasma concentration of amino-terminal pro-brain natriuretic peptide in chronic heart failure: prediction of cardiovascular events and interaction with the effects of rosuvastatin: a report from CORONA (Controlled Rosuvastatin Multinational Trial in Heart Failure).J Am Coll Cardiol - Abstract - Dunselman ✝, dr. P.H.J.M. [inactief]; Cornel, prof. dr. J.H. - CORONA - Heart failure November 2009
• Predictors of fatal and non-fatal outcomes in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): incremental value of apolipoprotein A-1, high-sensitivity C-reactive peptide and N-terminal pro B-type natriuretic peptide.Eur J Heart Fail - Abstract - Dunselman ✝, dr. P.H.J.M. [inactief]; Cornel, prof. dr. J.H. - CORONA - Heart failure March 2009
• Rosuvastatin in older patients with systolic heart failure.N Engl J Med - Abstract - Dunselman ✝, dr. P.H.J.M. [inactief]; Cornel, prof. dr. J.H. - CORONA - Heart failure November 2007